Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment method of a number of myeloma. Its synthesis or research is essential for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the output method and making sure higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is made use of to treat breast cancer, and these intermediates are linked to its production.
Fulvestrant Intermediates: Irinotecan hydrochloride trihydrate Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS CAS NO.154229-19-3 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have numerous applications, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is associated with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to deal with form two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).